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检测了64例肝硬化患者的血小板计数,血块退缩试验,血小板粘附试验,血小板聚集试验,血小板因子皿活性,结果发现:29例(45.3%)血小板计数减少.另外35 例血小板计数正常患者中,10例(28.4%)血小板粘附试验降低,25例(71.4%)血小板聚集试验降低.19例(54.4%)血小板因子Ⅲ活性减弱,这变化与肝功能损害的程度有关.在肝功能Child分级中,A、B、C级各组间血小板功能的异常有显著差异(x~2=10.1164,P<0.01),提示肝硬化患者存在血小板功能异常,血小板功能检查也可作为检测肝功能损害程度的辅助指标.
Sixty-four patients with cirrhosis were tested for platelet count, clot retraction test, platelet adhesion test, platelet aggregation test, and platelet activity. The results showed that 29 patients (45.3%) had a decreased platelet count, and 35 patients with normal platelet count , Platelet adhesion test was reduced in 10 cases (28.4%), and platelet aggregation test in 25 cases (71.4%) was decreased.The activity of platelet factor Ⅲ in 19 cases (54.4%) was decreased, which was related to the degree of liver dysfunction.In liver function Child There were significant differences in platelet function between groups A, B and C (x ~ 2 = 10.1164, P <0.01), suggesting that platelet dysfunction existed in patients with cirrhosis, and platelet function tests could also be used to detect liver dysfunction Degree of auxiliary indicators.