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下列原则可以作为预防与治疗某些职业中毒的病因学方法的依据:一、在机体内直接与毒物结合;二、对毒物的生物转化过程施加影响;三、使毒物引起的代谢障碍得到复原。应该认为,在治疗职业中毒的各个原则中,对毒物在体内的命运进行干予这一途径前景最好。近年来已证实,用络合物治疗多种重金属中毒有很高的疗效。在许多情况下,通过在体内与毒物结合的方法,可以减弱某些工业毒物的毒性。如氰化物中毒时,钴盐(其中包括二乙胺四乙酸钴)的解毒作用,在於钴能与氢氰酸结合,因而对含铁的组织酶起
The following principles can be used as a basis for the prevention and treatment of certain occupational poisoning etiology: First, the direct combination with poisons in the body; Second, exert an influence on the biotransformation process of poisons; Third, to make the metabolic disorders caused by poison recovered. It should be considered that the best way to deal with the fate of toxins in the body in the various principles of the treatment of occupational poisoning is the best. In recent years it has been confirmed that with complex treatment of a variety of heavy metal poisoning has a high effect. In many cases, the toxicity of certain industrial toxicants can be reduced by combining them with poisons in the body. In the case of cyanide poisoning, the detoxification of cobalt salts (including cobalt diethyldiethanolate) consists in that cobalt binds to hydrocyanic acid and hence iron-containing tissue enzymes