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蛇毒制剂较广泛地应用于急性脑梗塞的治疗,其成份的差异直接影响其治疗效果,东菱精纯克栓酶(DF—521)和精制去纤酶的疗效是否相同,国内报道很少。我们自1996年6月以来,对二种药物进行对照观察,现将研究方法和结果报告如下。 1 材料和方法 1.1 一般资料:脑梗塞106例,男65例,女41例,年龄46～75岁,平均62.3岁;病程3～48小时。随机分为DF—521及精制去纤酶治疗组,前者52例,后者54例,再根据发病至治疗时间分为两个亚组(1)≤24小时组,(2)25～48小时组。 1.2 病例选择:均为住院病人,符合全国第二次脑血
Snake venom preparations more widely used in the treatment of acute cerebral infarction, the composition of the direct impact on the treatment of its effect, Dongling refined Kexu enzyme (DF-521) and refined defibrase efficacy are the same, rarely reported in the country. We have compared the two drugs since June 1996, and the research methods and results are reported below. 1 Materials and Methods 1.1 General Information: 106 cases of cerebral infarction, 65 males and 41 females, aged 46 to 75 years, mean 62.3 years; duration of 3 to 48 hours. Divided into DF-521 and refined defibrase therapy group, the former 52 cases, the latter 54 cases, according to the onset to treatment time is divided into two subgroups (1) ≤ 24 hours group, (2) 25 ~ 48 hours group. 1.2 Case Selection: All inpatients, in line with the second national cerebral blood