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重症肝炎是病毒性肝炎的严重型,其发病率不高,约占病毒性肝炎病例的1％左右,但病死率较高。多发生在青壮年,儿童较少,流行期间妊娠妇女伴发重症肝炎者常见。重症肝炎在临床上与病理上分为急性重症肝炎、亚急性重症肝炎和慢性重症肝炎三种类型。重症肝炎主要表现为肝脏合成功能及解毒功能突然减退或停止,造成复杂的代谢障碍,免疫反应及肝性脑病。而在肝功衰竭的各种症状中以脑病昏迷最为明显。半数以上的重症肝炎病人死于脑水肿。
Severe hepatitis is a severe type of viral hepatitis, its incidence is not high, accounting for about 1% of cases of viral hepatitis, but higher mortality. Occurred in young adults, children less popular during pregnancy women with severe hepatitis are common. Severe hepatitis in clinical and pathological is divided into acute severe hepatitis, subacute severe hepatitis and chronic severe hepatitis three types. Severe hepatitis mainly manifested as a sudden decrease or stop of liver synthesis and detoxification function, resulting in complicated metabolic disorders, immune response and hepatic encephalopathy. In the various symptoms of liver failure in patients with cerebral disease coma most obvious. More than half of patients with severe hepatitis die of cerebral edema.