Quantitative Mitochondrial Proteomics Study on Protective Mechanism of Grape Seed Proanthocyanidin E

• 作 者: LU Wei-da QIU Jie ZHAO Gai-xia
• 机 构: KeyLaboratoryofCardiovascularProteomicsofShandongProvince,InstituteofPharmacology
• 出 处: 高等学校化学研究：英文版
• 发表日期: 2012年6期
• 关键词: 缺血 再灌注 葡萄籽原花青素 蛋白质组学 线粒体蛋白质 氧化损伤 心脏模型 保护作用 分子机制 Grape seed proanthocyanidin extr
• 基金项目: Supported by the National Natural Science Foundation of China（Nos.30700884,30873145）, the Distinguished Middle-aged and Young Scientist Encourage and Reward Foundation of Shandong Province,China（No.BS

Cardiac ischemia/reperfusion(I/R) injury is a critical condition,often associated with high morbidity and mortality.The cardioprotective effect of grape seed proanthocyanidin extracts(GSPE) against oxidant injury during I/R has been described in previous