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由甲氧羰基亚甲基三苯胂(Ⅰ)和碘甲烷生成的碘化α-甲基甲氧羰基亚甲基三苯钟(Ⅱ)与甲醇钠作用后,可形成α-甲基甲氧羰基亚甲基三苯胂(Ⅲ)。而甲氧羰基亚甲基三苯胂(Ⅰ)与苄溴形成的溴化α-苄基钟盐(Ⅳ)可与另一分子甲氧羰基亚甲基三苯胂(Ⅰ)进行叶立德交换反应,形成α-苄基甲氧羰基亚甲基三苯肿(Ⅶ)。这些α-烃基取代的胂叶立德(Ⅲ)和(Ⅶ)均可与芳醛缩合并立体选择地生成芳基与酯基处于反位的三取代烯酸酯,水解后可得相应的烯酸。
The α-methylmethoxycarbonylmethylenetrimethylene iodide (Ⅱ) formed by methoxycarbonylmethylenetriphenylarsine (Ⅰ) and methyl iodide can react with sodium methoxide to form α-methylmethoxy Carbonylmethylenetriphenylarsine (Ⅲ). However, the α-benzyl bromide (IV) which is formed by the reaction of methoxycarbonylmethylenetriphenylarsine (Ⅰ) with benzyl bromide can be reacted with another molecule of methoxycarbonylmethylenetriphenylarsine (Ⅰ) Alpha] -benzylmethoxycarbonylmethylenetetrahydrofuran (VII) is formed. These a-hydrocarbon-substituted arsonium ylides (III) and (VII) can both condense with aryl aldehydes and stereoselectively generate trisubstituted acid esters whose aryl groups are in transposition with the ester groups, and hydrolyze to give the corresponding acid acids.