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用三氟甲磺酸镱和配体共同催化吲哚与β-硝基烯的Friedel-Crafts反应,从而发展了一条简捷新颖地合成天然产物中广泛存在的3-取代吲哚衍生物的方法.该催化剂有反应条件温和、操作简单和价格较低等优点.
The Friedel-Crafts reaction of indoles with β-nitro-olefins catalyzed by ytterbium triflate and ligands has led to the development of a simple and novel method for the synthesis of 3-substituted indole derivatives widely found in natural products. The catalyst has the advantages of mild reaction conditions, simple operation and low price.