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美国波士顿大学医学院人类遗传学中心主任奥布里·朱伦斯基博士，对二万多名孕妇参加的历时３年的一项研究表明，在妊娠头６周服用含有叶酸的多种维生素的妇女，可使婴儿患所谓神经管缺陷的危险减少５０％～７０％。朱伦斯基博士指出，这项研究是同类研究中最肯定的研究成果。
Aubrey Jurantzki, director of the Center for Human Genetics, Boston University School of Medicine, a three-year study of more than 20,000 pregnant women showed that taking folic acid-containing multivitamins in the first 6 weeks of pregnancy Women can reduce their risk of developing so-called neural tube defects by 50% to 70%. Dr. Jujunski pointed out that this study is the most affirmative study of its kind.