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本文把60例60岁以上,具有大便次数减少和(或)粪便干燥难排,每周排便次数≤3次,并剔除因器质性疾病引起的便秘患者,随机平均分为3组。第1组患者口服胃肠动力药普瑞博思5mg,每d3次;第2组患者口服沙棘籽中提取的纯天然,具有润滑性的沙棘油10ml,每d3次;第3组患者上述2种药物联合服用。3组用药次数、方法、时间均相同,8周为1疗程,分别于治疗前、治疗后第1、2、4、8周记录每周大便次数和不良反应。疗程结束时查血、尿、粪常规和肝、肾功能。疗效判定标准是在服药后2周、4周、8周时,大便次数达到每周3次以上,其疗效分别是很
In this paper, 60 patients over the age of 60, with reduced stool frequency and / or excrement was difficult to discharge, defecation frequency ≤ 3 times per week, and excluding organic diseases caused by organic constipation patients were randomly divided into three groups. Group 1 patients oral gastrointestinal motility drug pregabalin 5mg, d3 times each; group 2 patients oral administration of seabuckthorn seed extract of natural, lubricated seabuckthorn oil 10ml, d3 times each; the third group of patients with the above two Drugs taken together. Three groups of medication times, methods, time are the same, 8 weeks for a course of treatment, respectively, before treatment, 1, 2, 4, 8 weeks after treatment records stool frequency and adverse reactions per week. At the end of treatment check blood, urine, fecal routine and liver and kidney function. The curative effect of the standard is 2 weeks after taking medicine, 4 weeks, 8 weeks, stool frequency reaches more than 3 times per week, the effect is very