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药物性肝损伤(DILI)是目前最常见的肝病之一,随着临床用药种类的日益增加,引起DILI的药物也越来越多,由于其病理学改变的不同,临床分型为肝细胞损伤型、胆汁淤积型、混合型。本文对99例DILI进行回顾性观察,对是否合用熊去氧胆酸(UDCA)进行临床疗效分析。资料与方法1.一般资料收集2008年1月-2012年12月在我院住院的99例DILI患者,病例均符合国际医学科学组织理事会DILI诊断建议标准[1]:(1)血清
Drug-induced liver injury (DILI) is one of the most common liver diseases. As the types of clinical medicine increase, the drugs that cause DILI are also more and more. Due to the different pathological changes, the clinical classification is hepatocellular injury Type, cholestasis type, mixed type. In this paper, 99 cases of DILI were retrospectively observed, whether the combination of ursodeoxycholic acid (UDCA) for clinical efficacy analysis. Materials and Methods 1. General Information Collection 99 cases of DILI patients hospitalized in our hospital from January 2008 to December 2012 were all in accordance with the DILI diagnostic criteria of the International Council of Medical Science Organizations [1]: (1) Serum