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目的:了解贵州省毕节地区燃煤污染型地方性氟中毒非干预区-鸭池镇下坝村与干预区-长春镇长春乡人群的乙型肝炎病毒(HBV)感染状况与流行趋势以及血氟含量。方法:采用酶联免疫吸附试验(ELISA)方法进行HBV血清学标志物检测,酶标仪分析HBV血清学结果;采用氟离子选择电极法测定血氟含量。结果:共调查汉族人群532人,检出HBV感染403例,感染率高达75.75%;其中高血氟人群检出HBV感染326例,感染率为68.78%;正常血氟人群检出HBV感染42例,感染率为65.63%。结论:贵州毕节鸭池镇下坝村与长春镇长春乡均具有较高的HBV感染率及血氟含量。
Objective: To understand the status and prevalence of Hepatitis B virus (HBV) infection and the prevalence of endemic fluorosis in coal-contaminated endemic fluorosis in Bijie Prefecture, Guizhou Province - Xiaba Village and intervention area of Duchi Town - Changchun Township, Changchun Town, content. Methods: HBV serological markers were detected by enzyme-linked immunosorbent assay (ELISA), HBV serology was analyzed by microplate reader, and fluoride content was measured by fluoride ion selective electrode method. Results: A total of 532 Chinese Han population were detected, 403 cases of HBV infection were detected, the infection rate was as high as 75.75%; among them, 326 cases of HBV infection were detected in high blood fluoride population, the infection rate was 68.78%; 42 cases of HBV infection were detected in normal blood fluoride population , The infection rate was 65.63%. Conclusion: Both Xiaba Village and Changchun Township, Changchun Town, Bijie County, Guizhou Province all have high HBV infection rate and blood fluoride content.