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目的评估肌层浸润性膀胱癌术中放疗的疗效及安全性。方法 37例肌层浸润性膀胱癌患者,手术中将肿瘤切除后,直视下用直线加速器给予一次性剂量照射,观察伤口愈合、肿瘤复发与无瘤生存时间。结果中位随访时间47个月,无伤口感染及延期愈合发生。37例中,10例分别于6-30个月膀胱腔内肿瘤复发,经尿道膀胱肿瘤电切术治疗后7例未再复发;共6例出现膀胱外转移性复发。结论浸润性膀胱癌术中放疗是一种保留膀胱的安全有效的治疗方法。
Objective To evaluate the efficacy and safety of intraoperative radiotherapy in myometrial invasive bladder cancer. Methods Thirty - seven patients with myometrial invasive bladder cancer were treated with one - time dose radiation with a linear accelerator under direct vision after resection of the tumor. The wound healing, tumor recurrence and tumor - free survival were observed. Results The median follow-up time was 47 months without wound infection and delayed healing. Among the 37 cases, 10 cases recurred in the bladder cavity at 6-30 months. Seven cases had no recurrence after transurethral resection of the bladder tumor. A total of 6 cases had recurrent bladder recurrence. Conclusion Intraoperative radiotherapy for invasive bladder cancer is a safe and effective treatment for bladder retention.