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有关文献报导异位性皮炎是一种T-抑制细胞(Ts)活性降低的细胞介导免疫功能障碍性疾病,许多作者把Ts缺陷和血清IgE增高联系起来。外周血单克隆抗体研究结果表明OKT_3~+和所有成熟的T细胞,OKT_4~+和T辅助细胞(T_H)和OKT_8~+和Ts抗原有关。本文报导了异位性皮炎患者外周血中OKT_3~+、OKT_4~+、OKT_8~+研究的结果和B细胞数、淋巴细胞转化试验及IgE的量,共查21例,男10、女11,年龄16~73岁,大多数患者年幼时曾有渗出性素质和本人或家族变态反应的病史,其中10例伴变
It has been reported that atopic dermatitis is a cell-mediated immune dysfunction with reduced T-suppressor (Ts) activity and many authors correlate Ts deficiency with elevated serum IgE. The results of peripheral blood monoclonal antibody showed that OKT_3 ~ + was related to all mature T cells, OKT_4 ~ + and T helper cells (T_H) and OKT_8 ~ + and Ts antigens. This paper reports the results of OKT_3 ~ +, OKT_4 ~ + and OKT_8 ~ + in peripheral blood of patients with atopic dermatitis, and the results of B cell number, lymphocyte transformation test and IgE amount. A total of 21 males, 10 males and 11 females, Age 16 to 73 years old, most patients had exudative quality of childhood and their own or family history of allergy, of which 10 cases with change