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通过235例I型糖尿病临床资料分析发现该病好发于中老年人,男性为多,并发周围神经病变则以女性为多,且发病率有逐年迅速增加趋势。临床症状不典型,且“三多一少”症状病例仅占48.09%,血脂与血脂蛋白异常率较高,占80%,其中以甘油三脂为显,占72.4%,病情多为轻、中型。并发症以神经系统病变为多,占81.28%,周围神经病变占52.77%,脑卒中占28.51%,以缺血性脑梗塞为多,占76.12%,且易发生腔隙性脑梗塞。并发症与病情轻重,病程长短无明显关系。作者并对糖尿病并发神经系病变的机理进行了讨论。
The clinical data of 235 cases of type I diabetes mellitus showed that the disease predisposed to middle-aged and elderly people, with more peripheral neuropathy and more women, and the incidence increased rapidly year by year. The clinical symptoms were not typical, and the symptoms of “three more and one less” accounted for only 48.09% of the cases. The rates of dyslipidemia and lipoprotein were higher, accounting for 80% of the cases, of which triglyceride was significant (72.4%) For light, medium. Complications of nervous system lesions were more, accounting for 81.28%, peripheral neuropathy accounted for 52.77%, stroke accounted for 28.51%, mostly ischemic cerebral infarction, accounting for 76.12%, and prone to Lacunar infarction. Complications and severity of disease duration no significant relationship. The authors also discussed the mechanism of diabetic neuropathy.