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目的探讨米非司酮配伍米索前列醇用于绝经后妇女取宫内节育器(IUD)的临床效果。方法将绝经后取IUD妇女100例随机分为观察组和对照组各50例。对照组行米索前列醇单独用药,观察组行米非司酮、米索前列醇联合用药,对比2组扩宫效果、取环效果。结果观察组扩宫有效率为90.0%高于对照组的68.0%,取环成功率为98%高于对照组的64%,差异均有统计学意义(P<0.05)。2组均未出现严重不良反应。结论米非司酮、米索前列醇联合用于围绝经期女性辅助取IUD软化扩张宫颈效果明显、手术顺利,可减轻受术者痛苦。
Objective To investigate the clinical efficacy of mifepristone and misoprostol in the treatment of post-menopausal women with intrauterine device (IUD). Methods 100 postmenopausal women with IUD were randomly divided into observation group and control group, 50 cases each. Control group, misoprostol alone, the observation group mifepristone, misoprostol combination therapy, compared with the two groups expansion effect, take the ring effect. Results The effective rate of dilatation in the observation group was 90.0% higher than 68.0% in the control group, and the successful rate of taking the ring was 98% higher than that in the control group (64%), the differences were statistically significant (P <0.05). No serious adverse reactions occurred in both groups. Conclusion Combination of mifepristone and misoprostol for peri-menopausal women with IUD softens and dilates the cervix obviously. The operation is smooth and the pain of the affected patients can be alleviated.