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用PCR技术对132例产妇乳汁作了HBV－DNA检测．其阳性率为53．8％。其中120例孕期乙肝血清学指标一项以上阳性和12例全阴性的产后5天之内的产妇乳汁中HBV－DNA阳性率分别为57．5％、16．7％，两组间阳性率有显著性差异（P＜0．005）：各项乙肝血清学指标阳性组间乳汁HBV－DNA阳性率无统计学差异（P＞0．05）。结果证实乳汁确实是HBV排泄的重要途径之一，孕期乙肝血清学指标阳性的母乳排毒率显著高于对照组，本文中对母乳中检出HBV-DNA的产妇的授乳问题，孕期乙肝血清学指标全阴性产妇通过乳汁感染新生儿的可能性和乳汁中HBV－DNA的检测方法作了讨论。
HBV-DNA was detected in 132 cases of maternal milk by PCR. The positive rate was 53.8%. The positive rates of HBV-DNA in maternal milk from 120 pregnant women with more than one hepatitis B serology index and 12 all-negative within 5 days postpartum were 57.5% and 16.7%, respectively. The positive rates of HBV-DNA Significant difference (P <0.005): There was no significant difference in the positive rate of HBV-DNA in breast milk among all HBV seropositive groups (P> 0.05). The results confirmed that breast milk is indeed one of the important ways of HBV excretion, hepatitis B serogroup positive pregnancy virus detoxification was significantly higher than the control group, breast milk in this study detected HBV-DNA maternal lactation, hepatitis B serology during pregnancy All-negative maternal milk through the possibility of infection of newborns and latex in the detection of HBV-DNA were discussed.