论文部分内容阅读
目的观察盐酸羟考酮缓释片治疗食管癌伴癌痛的不良反应及护理效果。方法选取赣南医学院第一附属医院2013年4月—2015年5月收治的食管癌伴癌痛患者148例。按照随机抽样法分为试验组与对照组,各74例。患者均予以盐酸氢考酮缓释片,对照组患者予以常规护理,试验组在对照组基础上实施综合护理。比较两组患者治疗与护理效果、生活质量评分、不良反应发生情况。结果试验组患者总缓解率高于对照组(P<0.05)。试验组患者生活质量评分高于对照组(P<0.05)。试验组不良反应发生率低于对照组(P<0.05)。结论应用盐酸羟考酮缓释片治疗的食管癌伴癌痛患者实施综合护理可有效减少不良反应发生率,改善患者临床病症,达到镇静止痛效果。
Objective To observe the adverse reactions and nursing effects of oxycodone hydrochloride sustained-release tablets in the treatment of esophageal cancer with cancer pain. Methods A total of 148 cases of esophageal cancer with cancer pain were selected from the First Affiliated Hospital of Gannan Medical College from April 2013 to May 2015. According to random sampling method divided into experimental group and control group, 74 cases each. Patients were treated with oxycodone hydrochloride sustained-release tablets, patients in the control group were routine care, the experimental group in the control group based on the implementation of comprehensive care. The treatment and nursing effects, quality of life score and adverse reactions were compared between the two groups. Results The total remission rate of the experimental group was higher than that of the control group (P <0.05). The quality of life in test group was higher than that in control group (P <0.05). The incidence of adverse reactions in the experimental group was lower than that in the control group (P <0.05). Conclusions The comprehensive nursing care of esophageal cancer patients with cancer pain treated with oxycodone hydrochloride sustained-release tablets can effectively reduce the incidence of adverse reactions, improve the clinical symptoms and achieve the analgesic effect of sedation.