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目的:分析血液透析滤过联合血液灌流治疗尿毒症脑病(UE)的临床效果。方法:选取该院2014年1月至2015年12月32例尿毒症脑病患者,运用随机分组法分为观察组(n=16)及对照组(n=16),对照组患者给予常规血流透析治疗,观察组患者采用血液透析滤过联合血液灌流治疗,科学评估两组患者临床治疗效果。结果:观察组治疗有效率为87.50%,高于对照组的50.00%;观察组患者的Cr、K~+、BUN、PTH、β_2-MG水平低于对照组。结论:在尿毒症脑病治疗过程中,采用血液透析滤过联合血液灌流治疗,有利于缓解临床症状,提高尿毒症毒素清除率,达到治疗目的。
Objective: To analyze the clinical effect of hemodiafiltration combined with hemoperfusion on uremic encephalopathy (UE). Methods: Thirty-two uremic encephalopathy patients from January 2014 to December 2015 in our hospital were randomly divided into observation group (n = 16) and control group (n = 16). Patients in control group were given routine blood flow Dialysis treatment, observation group patients with hemodiafiltration combined with hemoperfusion treatment, the clinical evaluation of two groups of patients scientifically. Results: The effective rate of observation group was 87.50%, which was higher than that of control group (50.00%). The levels of Cr, K ~ +, BUN, PTH and β_2-MG in the observation group were lower than those in the control group. Conclusion: During the treatment of uremic encephalopathy, hemodiafiltration combined with hemoperfusion can relieve the clinical symptoms, improve the clearance rate of uremic toxins and achieve the therapeutic goal.