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凝血酶原活动度(PTA)是检测肝脏凝血机制障碍的一项敏感指标,尤其是重型肝炎患者,根据PTA值可判断肝细胞坏死的严重程度及其预后。本文就重型肝炎PTA的动态变化与其他肝功能检查及出血预后的关系进行综合分析。1 材料与方法1·1 研究对象35例重肝患者均为我院1994～1996年的住院病人。男22例,女13例,年龄6～73岁,平均44岁。其中急重肝2例,亚重肝11例,慢重肝22例。除临床症状、体征的观察外,每例患者入院时查PTA。ALT和血清胆红素(SB),
Prothrombin activity (PTA) is a sensitive indicator of the disorder of hepatic clotting mechanisms, especially in patients with severe hepatitis. The severity of hepatocellular necrosis and its prognosis can be judged by PTA. This article analyzes the dynamic changes of PTA in severe hepatitis and other liver function tests and the relationship between bleeding prognosis. 1 Materials and Methods 1.1 Study Subject 35 cases of patients with severe liver in our hospital from 1994 to 1996 inpatients. 22 males and 13 females, aged 6 to 73 years, mean 44 years old. Two cases of acute severe hepatitis, 11 cases of sub-heavy liver, 22 cases of chronic severe liver. In addition to the clinical symptoms and signs of observation, each patient was admitted to check PTA. ALT and serum bilirubin (SB),