Antidepressant mechanism of Jieyu No. 1 decoction in a rat model of depression

• 作 者: Liping Zhang Li Wu Meng Xia Xu
• 机 构: DepartmentofBasicTheoryofTraditionalChineseMedicine
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2011年18期
• 关键词: 大鼠模型 抑郁症 汤剂 促肾上腺皮质激素 白细胞介素 机制 海马CA3区 异常行为 modified Wendan decoction depression
• 基金项目: Supported by： the National Natural Science Foundation of China, No. 30660231＊

Rats were subjected to unpredictable chronic stress and isolation-induced depression, and were then intragastrically perfused with Jieyu No.1 decoction or amitriptyline water solution for 21 consecutive days. Open-field test showed that Jieyu No.1 decocti