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目的：评价多发骨髓瘤病人不同形式摄取９９ｍ Ｔｃ Ｍ Ｉ Ｂ Ｉ的发病率及其与临床状态和疾病分期的关系，并尝试进一步明确骨髓摄取９９ｍ Ｔｃ Ｍ Ｉ Ｂ Ｉ的意义。方法：选多发骨髓瘤病人 ３９ 例，其中缓解期 １０例，活动期 ２９ 例（Ⅰ、Ⅱ、Ⅲ期分别为 １３、１０、６ 例）。静脉注射 ５５５ Ｍ Ｂｑ ９９ｍ Ｔｃ Ｍ Ｉ Ｂ Ｉ后 １０ 分钟和 １、２、４小时分别行全身前、后位显像，每体位采集 ７ 分钟。９９ｍ Ｔｃ Ｍ Ｉ Ｂ Ｉ摄取形式分为正常摄取（ Ｎ）、弥漫性摄取（ Ｄ）、局部明显摄取（ Ｆ）和弥漫摄取与局部摄取并存（ Ｄ＋ Ｆ）四种。显像结果总评分为摄取范围评分（０～３）与强度评分（０～３）之和。同时做了血液及生化检查。结果：９９ｍ Ｔｃ Ｍ Ｉ Ｂ Ｉ摄取的不同形式所发生的例数分别为 Ｎ７、 Ｄ１８、 Ｆ２、 Ｄ＋ Ｆ１２；所有活动期病人均异常摄取９９ｍ Ｔｃ Ｍ Ｉ Ｂ Ｉ（总评分＞ ２，其中Ⅰ期 Ｄ 为 １２例、 Ｄ＋ Ｆ为 １ 例，Ⅱ期 Ｄ 为 ２ 例、 Ｄ＋ Ｆ为 ６ 例、 Ｆ为２ 例，Ⅲ期 Ｄ 为 １ 例、 Ｄ＋ Ｆ为 ５ 例，与缓解期摄取形式（总评分≤２， Ｎ 为 ７ 例、 Ｄ 为 ３ 例），差异显著（ Ｐ＜０．００１）。所有病人９９
Objective: To evaluate the incidence of different forms of 99m Tc-M I B I in patients with multiple myeloma and their relationship with clinical status and disease stage, and try to further clarify the significance of bone marrow uptake of 99m Tc-M I B I. Methods: Thirty-nine patients with multiple myeloma were selected. Among them, 10 were remission and 29 were active (stage I, II and III were 13, 10 and 6, respectively). Intravenous injection of 555 M Bq 99m Tc M I B I 10 minutes and 1, 2, 4 hours after the whole body before and after imaging, each body position for 7 minutes. 99m Tc M I B I intake is divided into normal intake (N), diffuse uptake (D), local significant uptake (F) and diffuse uptake and local uptake (D + F) four. Scoring results of the total score for the intake range of scores (0 ~ 3) and the strength score (0 ~ 3) and. At the same time did a blood and biochemical tests. Results: The incidences of different forms of 99m Tc-M I B I intake were N7, D18, F2 and D + F12, respectively. All of the patients with active stage had abnormal 99m Tc-M I B I intake (total score> 2, Stage D was 12 cases, D + F was 1 case, stage D was 2 cases, D + F was 6 cases, F was 2 cases, stage III was D, and D + F was 5 cases, and remission ingestion form Total score≤2, N = 7, D = 3), the difference was significant (P <0.001) .All the patients