低频下降型突发性聋内淋巴积水特征分析

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目的:探讨低频下降型突发性聋的临床特点与内耳磁共振(MR)钆造影内淋巴积水的相关性。方法:连续选取2019年7月至2020年1月在复旦大学附属眼耳鼻喉科医院门诊或病房住院治疗的成人单侧低频下降型突发性聋患者,进行听力学、内耳MR钆造影检查,给予相同的治疗方案,记录疗效,并随访3个月以上。分析伴发症状、耳聋各频率程度等因素与患者内淋巴积水的相关性。结果:纳入患者48例,男18例,女30例,年龄21~52(37.3±10.0)岁;均为单侧发病,其中左耳28例,右耳20例;病程均≤2周。内淋巴积水组14例,包括前庭积水6例,耳蜗积水2例,耳蜗与前庭均积水6例。与无积水组(34例)比较,内淋巴积水组头晕发生率高(6/14比0/34,n P0.05);内淋巴积水组在1 000、2 000 Hz听力值均较无积水组差(均n P<0.05)。听力疗效总有效33例(68.8%),无效15例(31.2%),其中11例内淋巴积水患者听力预后差。n 结论:低频下降型突发性聋患者中,与无内淋巴积水者比较,有内淋巴积水的患者头晕发生率较高,在1 000、2 000 Hz听力值更差,预后较差。“,”Objective:To investigate the correlation between the clinical features of low-frequency sudden deafness and endolymphatic hydrops on gadolinium contrast in the inner ear.Methods:From July 2019 to January 2020, adult patients with unilateral low-frequency sudden deafness who were hospitalized in the outpatient clinic or ward of the Department of Otorhinolaryngology, Eye and ENT Hospital of Fudan University were selected and examined by audiology and gadolinium magnetic resonance (MR) angiography of inner ear. The same treatment plan was given, and the curative effect was recorded and followed up for more than 3 months. SPSS 20.0 software was used to analyze the correlation between the accompanying symptoms, deafness, and endolymphatic hydrops.Results:A total of 48 patients were included in the study, including 18 males and 30 females. The age ranged from 21 to 52 (37.3±10.0) years. All of them were unilateral, including 28 cases of left ear and 20 cases of right ear. The course of the disease was less than 2 weeks in all cases. The endolymphatic hydrops group included 14 cases, including vestibular hydrocele (6 cases), cochlear hydrops (2 cases), and cochlear and vestibular hydrops (6 cases). The incidence of dizziness in the endolymphatic hydrops group was higher than that in the non-hydrops group (6/14 vs 0/34, n P0.05). The hearing in the endolymphatic hydrops group was worse than that in the non-hydrops group at 1 000 and 2 000 Hz.n Conclusion:Compared with those without endolymphatic hydrops, patients with hydrops tend to have a higher incidence of dizziness, worse hearing at 1 000 and 2 000 Hz, and a worse prognosis.
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