论文部分内容阅读
目的描述55岁以下的视网膜中央静脉阻塞(CR-VO)患者的临床进程。设计和方法回顾性非比较性的连续病例分析。复习了67例患者的人口统计学、影像、临床和视力数据。对其中随访6个月以上(平均29.2个月)的病例资料进行了统计学分析。主要结果测定最佳矫正视力和眼内新生血管形成的发病率。结果在连续的67例(男性55%,平均年龄45岁)患者中,视力平均为20/50。其中45例(67%)患者被查出至少有1种全身性疾病。在57例随访6个月以上的患者中,最终视力20/40(含)以上的占42%,20/50-20/100的占18%,20/200(含)以下的占40%.在CRVO发病的3-6个月内,绝大部分患者出现了视力减退。在发病的12个月以后,出现视力提高的极少见。就诊视力在20/40(含)以上的22例患者中,36%的患者在最近的1次检查中视力下降到了20/400甚至更低。就诊视力在20/200-20/400的10例患者中,8例视力提高到20/60甚至更高。就诊视力在数指或者更差的6例患者中,没有1例视力得到改善。在CRVO发病的1-9个月内,10例(18%)患者被诊断为眼内新生血管形成。其中前节新生血管形成的患者有6例(11%),包括3例(5%)新生血管性青光眼。新生血管形成的发生与患者的性别、年龄、有无伴随疾病、症状的持续时间和就诊视力均没有明显关系。结论年轻患者的CRVO有着多变的临床过程?
Objective To describe the clinical course of patients under 55 years of age with central retinal vein occlusion (CR-VO). Design and methodology Retrospective non-comparative continuous case analysis. 67 patients were reviewed demographic, imaging, clinical and visual data. Cases were followed up for more than 6 months (average 29.2 months) of the case data were analyzed. The main results measure the best corrected visual acuity and the incidence of intraocular neovascularization. Results In a continuous series of 67 patients (55% of men with a mean age of 45 years), visual acuity averaged 20/50. Of these, 45 (67%) were diagnosed as having at least one systemic disease. Among 57 patients who were followed up for more than 6 months, 42% had final visual acuity of 20/40 (inclusive), 18% (20/50-20%) and 40% (20/20%) had final visual acuity. Within 3-6 months of the onset of CRVO, most patients develop vision loss. After the onset of 12 months later, there is very rare sight improvement. Of the 22 patients with a visual acuity above 20/40 (inclusive), 36% had visual acuity of 20/400 or less in a recent exam. Out of 10 patients with visual acuity of 20 / 200-20 / 400, visual acuity increased to 20/60 or even higher in 8 patients. Out of the 6 patients who were referred for visual acuity or worse, none of them improved their vision. Within 1-9 months of onset of CRVO, 10 (18%) patients were diagnosed with intraocular neovascularization. Six of these patients (11%) had anterior neovascularization, including 3 (5%) neovascular glaucoma. Neovascularization occurred with the patient’s gender, age, with or without the disease, the duration of the symptoms and treatment of visual acuity were not significantly related. Conclusion CRVO in young patients has a variable clinical course?