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目的:探讨输血前后血浆D-二聚体水平作为肿瘤患者输血前后评估指标的临床意义。方法:按输血效果以及输血量和输血次数进行分组,比较输血前后患者血浆D-二聚体含量变化,对检测结果进行统计学分析。结果:143例经输血治疗的肿瘤患者输血后血浆D-二聚体含量均明显增加,输注红细胞2U以上或多次输血的肿瘤患者血浆D-二聚体含量显著增加(P<0.01),具有统计学意义。结论:血浆D-二聚体含量监测可作为肿瘤患者科学、合理输血的循证依据,并以此制定个性化的输血策略。
Objective: To investigate the clinical significance of plasma D-dimer level before and after blood transfusion as an index for evaluation of tumor patients before and after transfusion. Methods: According to the blood transfusion, blood transfusion and transfusion number, the plasma D-dimer levels in patients before and after transfusion were compared, and the results were statistically analyzed. Results: The blood plasma D-dimer levels of 143 transfused patients were significantly increased. The plasma D-dimer levels were significantly increased in patients with transfused tumors more than 2U (P <0.01) has statistical significane. Conclusion: The monitoring of plasma D-dimer level can be used as evidence base for scientific and rational blood transfusion in patients with cancer and to formulate a personalized transfusion strategy.