论文部分内容阅读
目的对常用弥散性血管内凝血(DIC)实验室诊断指标的敏感性、特异性及其改变的意义进行比较评估。方法采用了一般实验室可行的常用DIC实验室诊断指标如凝血酶原时间(PT),纤维蛋白原定量(Fbg), D二聚体(DD),鱼精蛋白副凝固试验(3P)等7项试验。结果检测120例临床病例PT阳性率是84.1%,Fbg 阳性率是81.8%,DD阳性率是81.8%,3P阳性率是70.5%。结论常用DIC实验室诊断指标简便实用,并具有一定的特异性和敏感性,但就诊断DIC而言均存在较高的假阳性与假阴性,因此进行连续、动态观察以及结合临床综合分析诊断至关重要。
Objective To compare and evaluate the sensitivity, specificity and the significance of the changes in laboratory diagnostic indexes of disseminated intravascular coagulation (DIC). Methods Common laboratory diagnostic criteria such as prothrombin time (PT), fibrinogen quantitation (Fbg), D dimer (DD) and protamine secondary coagulation assay (3P) were used. Test Results The positive rate of PT was 84.1% in 120 clinical cases, the positive rate of Fbg was 81.8%, the positive rate of DD was 81.8% and the positive rate of 3P was 70.5%. Conclusion DIC laboratory diagnostic indicators commonly used simple and practical, and has a certain specificity and sensitivity, but in terms of the diagnosis of DIC are high false positives and false negatives, so continuous, dynamic observation combined with clinical diagnosis of comprehensive analysis to Important.