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治疗应用高血糖素不能口服,只能作注射用,作用时间短,一般用静注或静滴。静脉注射后,经1~3分钟出现作用,5~7分钟达高峰,作用只能维持10~15分钟,故要维持较长时间,一般采用静滴。给药方法:由于高血糖素毒性小,作用时间又短,静注一般用3~5毫克约20秒钟内注完(制剂一般为每毫升含1毫克),如果未发生恶心,可30~60分钟重复一次。静滴剂量为每小时5~10毫克,可连续静滴24~48小时以上,除因在静滴过程中发生恶心和可能呕吐外,不必停药。根据临床使用的结果,连续静滴是取得良好疗效的方法。 (一)高血糖素对心脏疾患的应用由于高血糖素具有强心而又优于一般强心药物
Glucagon treatment can not be applied orally, only for injection, the role of time is short, usually with intravenous or intravenous infusion. After intravenous injection, the role of 1 to 3 minutes, 5 to 7 minutes up to the peak, the role can only be maintained for 10 to 15 minutes, it is necessary to maintain a long time, the general use of intravenous drip. Method of administration: Due to the low toxicity of glucagon, the action time is short, intravenous injection usually 3 ~ 5 mg within about 20 seconds Note (preparation is generally 1 mg per ml), if no nausea, 30 ~ Repeat for 60 minutes. Intravenous doses of 5 to 10 mg per hour, continuous intravenous infusion of more than 24 to 48 hours, except in the process of intravenous nausea and vomiting may occur, do not have to stop. According to the results of clinical use, continuous intravenous infusion is to obtain good curative effect. (A) the application of glucagon on heart disease Because glucagon has a cardiac and superior to the general cardiac drug