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目的了解衡阳市先天性心脏病发生率及其动态变化,为制定先天性心脏病的预防措施提供依据。方法以医院为基础的出生缺陷监测方法收集资料,对2002-2009年衡阳市围生儿先天性心脏病监测资料进行分析。结果 8年来衡阳市围生儿先天性心脏病平均发生率为3.13/万,经卡方检验,有上升趋势(P<0.01)。男性发生率为3.55/万,女性发生率为2.63/万,两者差异无显著性(P>0.05);城镇发生率为6.11/万,农村发生率为1.83/万,两者差异有统计学意义(P<0.01);四季节发生率分别为4.86/万、1.57/万、1.68/万、5.00/万,四季节之间差异有统计学意义(P<0.01);孕妇<20岁、20~25岁、25~30岁、30~35岁和≥35岁组发生率分别为9.75/万、2.61/万、3.70/万、1.36/万、6.17/万,孕妇年龄组之间差异有统计学意义(P<0.01)。结论 8年来衡阳市围生儿先天性心脏病发生率呈上升趋势;城镇发生率高于农村;冬春季发生率高于夏秋季;孕妇年龄<20岁和≥35岁是先天性心脏病的高发年龄阶段。
Objective To understand the incidence and dynamic changes of congenital heart disease in Hengyang and to provide evidence for the prevention of congenital heart disease. Methods A hospital-based monitoring method of birth defects was collected to analyze the monitoring data of perinatal congenital heart disease in Hengyang during 2002-2009. Results The average incidence of congenital heart disease in perinatal infants in Hengyang during the past 8 years was 3.13 per 10 000. The chi square test showed an upward trend (P <0.01). The incidence of males and females was 3.55 / million and 2.63 / females, respectively. There was no significant difference between the two (P> 0.05). The incidence rate in urban area was 6.11 / million and that in rural areas was 1.83 / (P <0.01). The incidence rates of four seasons were 4.86 / 10000, 1.57 / 10000, 1.68 / 10000 and 5.00 / 000 respectively. There was a significant difference between the four seasons (P <0.01) The incidence rates of ~ 25 years old, 25 ~ 30 years old, 30 ~ 35 years old and ≥35 years old group were 9.75 per thousand, 2.61 per thousand, 3.70 per thousand, 1.36 per thousand, 6.17 per thousand, Significance (P <0.01). Conclusions The prevalence of congenital heart disease in Hengyang City has been increasing in recent 8 years. The incidence of congenital heart disease in urban areas is higher than that in rural areas. The incidence in winter and spring is higher than that in summer and autumn. The incidence of congenital heart disease in pregnant women <20 and 35 years old is high Age.