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作者从1971～1973年观察181例慢性肾盂肾炎(女121例,男60例),其中32％由膀胱或尿路感染上行所致,18％发生于慢性生殖系感染的基础上,4％由血行途径发生,2％是由于肠道感染,21％发生途径不明。仅仅11％的慢性肾盂肾炎来自急性肾盂肾炎,12％来自妊娠肾病,绝大多数则是原发的慢性肾盂肾炎。慢性肾盂肾炎的病因,单纯大肠杆菌占52％,有些则是在肠杆菌与葡萄球菌和肠球菌含并感染。但24％没有细菌生长。为了明确无菌性肾盂肾炎的发生,作者等用营养丰富的培养基进行尿培养,其阳性率由76％增加到84％。加醋酸鉈培养时,还可得到L型细菌的生长,这些资料说明,无菌性肾盂肾炎的说法是没有根据的。据文献报导,大肠杆菌含有异种ABO型抗原,能削弱机体的免疫防御反应,促进该细菌的生存。作者研究了55例患者尿中的干扰素,48例有不耐热的干扰素,7例有耐热的干扰素。据认为,耐热的干扰素的存在,是病毒感染的特征。在诊断方面,作
The authors observed 181 chronic pyelonephritis (121 female and 60 male) from 1971 to 1973, of which 32% were caused by upward urinary bladder or urinary tract infection and 18% occurred on the basis of chronic germ-line infection, with 4% Bloodstream occurred, 2% is due to intestinal infections, 21% of the unknown pathways. Only 11% of chronic pyelonephritis comes from acute pyelonephritis, 12% from pregnancy-induced nephropathy, and the vast majority are primary chronic pyelonephritis. The cause of chronic pyelonephritis, Escherichia coli accounted for 52%, while others are in Enterobacteriaceae and Staphylococcus aureus and enterococci infection. However, 24% did not grow bacteria. In order to clarify the occurrence of aseptic pyelonephritis, the authors used urine-enriched culture medium for urine culture, the positive rate increased from 76% to 84%. Adding thallium acetate incubation, but also get the growth of L-type bacteria, these data indicate that the statement of sterile pyelonephritis is unfounded. According to reports in the literature, E. coli containing different ABO-type antigen, can weaken the body’s immune defense response and promote the survival of the bacteria. The authors studied interferon in the urine of 55 patients, 48 patients with heat-labile interferons, and 7 patients with heat-tolerant interferons. It is thought that the presence of a heat-resistant interferon is characteristic of a viral infection. In diagnosis, make