乳腺增生中雌激素敏感性受体突变

来源 :国外医学(肿瘤学分册) | 被引量 : 0次 | 上传用户:NewMagic
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雌激素受体 (ER)为糖蛋白 ,在大多数乳腺癌发生过程中 ,雌激素及受体有着重要的作用。本实验发现ER一处基因突变 ,导致受体对激素的敏感性大大增高 ,作者对此做了分子生物学和细胞生物学方面的研究。首先在一个小样本 (4例 )的实验中发现 2例乳腺增生患者ER基因第 90 8位 Estrogen receptors (ERs) are glycoproteins that play an important role in the development of most breast cancers. This experiment found that a gene mutation in ER, resulting in receptor sensitivity to hormones greatly increased, the authors made a molecular biology and cell biology research. First, in a small sample (4 cases) of the experiment found two cases of breast hyperplasia patients ER gene 908
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