论文部分内容阅读
目的：了解美沙酮维持治疗中重入组受治者的入组前药物滥用特征，并观察其维持治疗情况。方法：选取广州市荔湾区门诊从开诊到2014年1月1日在治的重入组受治者作为观察对象，以其既往药物滥用情况及此后半年时间的治疗数据作为观察指标，并与维持服药3年以上的受治者同期治疗数据进行比较分析。结果：两组受治者首次吸毒年龄及注射行为比例差异有统计学意义（P1=0.008，P2=0.049），重入组在治者的服药剂量、服药参与率、尿检参与率低于对照组，且差异有统计学意义（ t=-2.937，P1=0.004；Z=-4.864，P2<0.001；Z =-4.936， P3<0.001）。而尿检阳性率高于对照组，且差异有统计学意义（ Z=2.541，P=0.012）。结论：美沙酮维持治疗中重入组与长期维持治疗受治者比较入组前注射行为比例更高，进入治疗后存在依从性较差的情况。“,”Objective:To explore thecharacteristics of drug abuse history and treatment behaviors among the re-enrolled patients receiving methadone maintenance.Methods:Subjects of this study were the patients who wereon methadone maintenance treatment (MMT) during January 1,2014 in theMethadone Maintenance Clinic in Liwan district of Guangzhou. Patients who had ever dropped out of MMT were selected as the study group,while patients who had been on MMT for more than three years as the control group. The history of drug abuse and the compliance of patients to MMT were compared between the two groups.Results:The age of first drug use is significantly different between two groups (?2=11.736,P=0.008).It is important to note a higher proportion of intravenous injection is found in the re-enrolled group (?2=6.025,P=0.049). Significant differences are found in the dosage of methadone, the proportion of attendance in MMT, the proportionof uptake of urine test and the proportion of positive urinalysis between the re-enrolled group and the control group ( t=-2.937,P=0.004; Z=-4.864,P<0.001;Z=-4.936,P<0.001; Z=2.541, P=0.012).Conclusion:We found a higher proportion of intravenous injection behaviors among the re-enrolled MMT participants, and more attention should be paid to their poor treatment compliance.