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目的:探讨原发于鼻腔鼻窦恶性T/NK细胞淋巴瘤的发病、诊断、治疗及预后。方法:对26例原发于鼻腔鼻窦恶性T/NK细胞淋巴瘤患者的临床诊断及治疗结果进行回顾性分析。结果:本组病例中,26例患者均经病理确诊为T/NK细胞淋巴瘤,平均随访16个月,死亡19例,从发病到死亡时间为2~28个月。结论:原发于鼻腔鼻窦恶性T/NK细胞淋巴瘤是结外非霍奇金淋巴瘤的一个独特类型,其恶性程度高,具有较高的侵袭性、独特的病理学及免疫学特征,而且临床上极易误诊,其治疗效果差,预后不佳。
Objective: To investigate the incidence, diagnosis, treatment and prognosis of primary malignant T / NK cell lymphoma in nasal sinuses. Methods: The clinical diagnosis and treatment of 26 patients with malignant T / NK cell lymphoma originated from nasal sinuses were analyzed retrospectively. Results: Twenty-six patients were diagnosed as T / NK cell lymphoma by pathology. Twenty-nine patients were followed up for an average of 16 months. The morbidity and mortality were 2 to 28 months. Conclusions: Malignant T / NK cell lymphoma is a unique type of extranodal non-Hodgkin’s lymphoma with a high degree of malignancy, high invasiveness, unique pathological and immunological characteristics, and Clinically easy to misdiagnosis, its poor treatment, poor prognosis.