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西沙必利(cisapride,Prepulsid,普瑞博思)为苯甲酰胺类化合物,是第三代胃肠道促动力药,通过选择性地促进肠肌层神经丛节后处乙酰胆碱的释放而影响整个胃肠道的运动活性,临床主要用于治疗胃轻瘫、反流性食管炎等症。近年来随着临床应用日益增多,不良反应也时有报道,兹介绍如下。
Cisapride (Prepapapid, Prepulsid) is a benzamide compound that is the third generation of gastrointestinal motility drug that affects the entire stomach by selectively promoting the release of acetylcholine after the myenteric plexus Intestinal motility, clinical mainly for the treatment of gastroparesis, reflux esophagitis embolism. In recent years, with the increasing clinical application, adverse reactions are also reported from time to time, are introduced below.