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目的探索脑血管造影术后血管痉挛的相关因素及对应的预防措施。方法选择2010年1月～2011年12月某院行脑血管造影检查的患者为研究对象,共计80例。对照分析不同因素情况下血管痉挛发生率,多元回归分析血管痉挛发生率与相关因素的相关性。结果技术操作熟练者发生率显著低于技术操作不熟练者(P﹤0.05),材料选择适合者发生率显著低于材料选择不适合者(P﹤0.05),操作时间长者发生率显著高于操作时间短者(P﹤0.05),存在特殊疾病者发生率显著高于不存在特殊疾病者(P﹤0.05),应用尿激酶者发生率显著低于未应用尿激酶者(P﹤0.05),应用尼莫地平者发生率显著低于未应用尼莫地平者(P﹤0.05)。血管痉挛发生率与技术操作、材料选择、尿激酶及尼莫地平呈负相关性,与操作时间及特殊疾病呈正相关性,差异有统计学意义(P﹤0.05)。结论脑血管造影术后发生血管痉挛的相关因素有:技术操作、材料选择、操作时间、特殊疾病、尿激酶及尼莫地平应用等,应在上述环境强化对应措施,以降低术后脑血管痉挛的发生率。
Objective To explore the related factors of vasospasm after cerebral angiography and corresponding preventive measures. Methods From January 2010 to December 2011, patients undergoing cerebrovascular angiography in a hospital were enrolled in this study, a total of 80 cases. The incidence of vasospasm was analyzed by comparing different factors, and the correlation between incidence of vasospasm and related factors was analyzed by multiple regression analysis. Results The incidence of skilled operation was significantly lower than that of inexperienced operation (P <0.05), the incidence of suitable material selection was significantly lower than that of unsuitable materials (P <0.05), and the incidence of elderly with operation time was significantly higher than that of unskilled (P <0.05). The incidence of special diseases was significantly higher than those without special diseases (P <0.05). The incidence of using urokinase was significantly lower than that without urokinase (P <0.05) The incidence of nimodipine was significantly lower than that of nimodipine (P <0.05). The incidence of vasospasm was negatively correlated with technical operation, material selection, urokinase and nimodipine, and was positively correlated with operation time and special diseases (P <0.05). Conclusions The related factors of vasospasm after cerebrovascular angiography include technical operation, material selection, operation time, special diseases, application of urokinase and nimodipine, etc. Corresponding measures should be strengthened in the above environment to reduce postoperative cerebral vasospasm The incidence of.