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目的了解某市当前乙肝高发县区居民的感染情况,为探索防治乙肝新方法提供详细的本底资料。方法采用以乙肝检测项目为主的居民健康体检,系统分析乙肝感染状况调查材料。结果该市乙肝高发县区的HbsAg阳性率为4.99%,农村高于城市;15岁以下人群HbsAg阳性率虽低,但农村明显高于城市,15岁及以上人群随年龄增长HbsAg阳性率逐步升高;男︰女HbsAg阳性率性别比为1.18︰1;工人、家务及待业的HbsAg阳性率高于其他职业人群。总体HbsAb阳性率低,0~14岁年龄组HbsAb阳性率为52.75%,低于全国平均水平。结论该市自2004年将乙肝疫苗纳入免疫规划以来,乙肝防控成效显著,但乙肝疫苗常规接种存在薄弱环节,农村尤甚;控制乙肝的关键措施在于提高成人乙肝疫苗的接种率;如何提高人群免疫效果值得进一步探讨。
Objective To understand the current prevalence of hepatitis B in some counties in a city and provide detailed background information for exploring a new method to prevent and treat hepatitis B. Methods The health examination of residents based on hepatitis B test was used to systematically analyze the investigation of hepatitis B infection. Results The positive rate of HbsAg was 4.99% in the high incidence area of Hepatitis B in the city, which was higher than that in the urban area. The positive rate of HbsAg in the population under the age of 15 was low, but the rural area was obviously higher than that in the urban areas. High; male: female HbsAg positive rate of sex ratio was 1.18: 1; workers, housework and unemployed HbsAg positive rate higher than other occupational groups. The overall positive rate of HbsAb was low, and the positive rate of HbsAb in the 0-14 age group was 52.75%, lower than the national average. Conclusion Since the hepatitis B vaccine was included in the immunization program in 2004, the prevention and control effect of hepatitis B in the city was significant. However, the conventional vaccination of hepatitis B vaccine is weak in rural areas, especially in rural areas. The key measures to control hepatitis B are to increase the vaccination rate of adult hepatitis B vaccine and how to increase the population Immune effects deserve further discussion.