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目前,巯甲丙脯酸(下简称巯丙)是治疗心衰的一种较好的血管扩张剂,在临床上应用广泛,得到大家的承认。但该药也有一定的不良反应。现以我院内科收治的15例心衰病人为例,来看巯丙的利与弊。 一、巯丙与强心、利尿药合用,疗效显著,能缩短纠正心衰时间。 我科择选的15例心衰病人,其病因不同(包括风心8例,肺心3例,扩张型心肌病4例),男6例女9例。年龄在44～73岁之间,心功能Ⅲ～Ⅳ级,症状体征典型。将巯丙与强心、利尿剂合用(巯丙量为75mg/日),用药后3～7天,约60％的病人心衰得到纠正;30％的病人在7～10天内心衰也同样得到纠正。平均在8天左右的时间内使心衰逐步缓解并治愈,较已往入院治疗的心衰时间缩短了5～10天。
Currently, captopril (hereinafter referred to as mercaptopril) is a good vasodilator for the treatment of heart failure, widely used in clinical, get everyone’s recognition. But the drug also has some adverse reactions. Now in our hospital medical treatment of 15 cases of heart failure patients, for example, look at the merits and disadvantages of mercap. First, the mercapril C and cardiac, diuretic combination, significant effect, can shorten the time to correct heart failure. Our department choose 15 cases of heart failure patients, its etiology (including 8 cases of wind heart, pulmonary heart in 3 cases, dilated cardiomyopathy in 4 cases), 6 males and 9 females. Age 44 to 73 years old, heart function Ⅲ ~ Ⅳ grade, typical symptoms and signs. Thioglycoprotein and cardiac, diuretic combined (captopril 75mg / day), 3 to 7 days after treatment, about 60% of patients with heart failure was corrected; 30% of patients within 7 to 10 days of heart failure is also the same Be corrected. On average, the heart failure is gradually relieved and cured over a period of about 8 days, which is 5 to 10 days shorter than that of the hospitalized heart failure.