论文部分内容阅读
目的 探讨影响冠状动脉 (冠脉 )慢性闭塞病变介入治疗成功的因素及其对预后的影响。方法 在 2 0 0 0年 6月至 2 0 0 3年 4月间对 5 2例冠脉慢性闭塞病变患者行经皮冠脉介入治疗 (PCI) ,其中 30例闭塞冠脉成功开通 (开通组 ) ,2 2例闭塞冠脉无法开通 (未开通组 )。比较两组的临床特点和预后。结果 与未开通组比 ,开通组高血压的发生率 (5 3%对 2 3% )较高 (P <0 .0 5 )。推测的血管堵塞时间较短 (P <0 .0 1) ,总胆固醇含量较低 ,分别为 (4 .8± 0 .85 )和 (5 .6± 1.5 )mmol/L(P <0 .0 5 ) ,闭塞病变呈平齐截断或有桥侧支或在分支开口附近或病变长度较长者比例较低 (17%对 4 5 % ,P <0 .0 5 ) ;随访期无胸痛胸闷者比例较高 (73%对 5 0 % ,P <0 .0 5 ) ;再次PCI ,外科冠脉旁路手术和再次住院的联合终点少 (13%对 36 % ,P <0 .0 5 )。结论 冠脉慢性闭塞病变的PCI成功率与推测的堵塞时间和闭塞病变的形态有关。闭塞病变开通者临床预后较好
Objective To explore the factors influencing the success of interventional therapy of chronic occlusion of coronary artery (coronary artery) and its influence on prognosis. Methods Between June 2000 and April 2003, 52 patients with chronic coronary artery occlusion underwent percutaneous coronary intervention (PCI). 30 patients with occlusive coronary artery were successfully opened (open group) , 22 cases of occlusion of the coronary artery can not be opened (not open group). The clinical features and prognosis of the two groups were compared. Results Compared with unopened group, the incidence of hypertension in open group (53% vs 23%) was higher (P <0.05). The presumed time of occlusion was shorter (P <0.01) and total cholesterol was lower (4. 8 ± 0.85) and (5.6 ± 1.5) mmol / L, respectively (P <0. 0 5). The occlusion lesion was flat or truncated or the posterior branch of the bridge or in the vicinity of the branch opening or lesion length was lower (17% vs 45%, P <0.05) (73% versus 50%, P <0.05). There was also a lower number of PCI surgeries compared with PCI (13% vs 36%, P <0.05). Conclusion The success rate of PCI in patients with chronic coronary artery occlusion is related to the presumed time of occlusion and the morphology of occlusion. Occlusive disease opened the clinical prognosis is good