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前已报道,我们用酶解法配合有机溶剂沉淀法从新鲜猪胎盘分离、纯化获得猪胎盘脂多糖。经药理实验证实本品能改善和提高机体的免疫功能,在临床上对老年性气管炎有良好防治效果,且无热原和过敏反应,已广泛应用于临床。现用鼠类脾淋巴细胞的组织培养实验证明,本品能明显地促进脾淋巴细胞的增殖。对脾淋巴细胞的DNA合成具有显著促进作用。其刺激指数约为9.3,最适刺激剂量为50～60μg/ml,最适刺激时间为48小时。同时发现本品也能促进脾淋巴细胞的蛋白质合成。在50μg/ml时,
It has been reported previously that we isolated and purified placenta lipopolysaccharide from fresh pig placenta by enzymatic hydrolysis combined with organic solvent precipitation. The pharmacological experiment confirmed that the product can improve and enhance the body’s immune function, and has a good clinical control effect on senile bronchitis, and no pyrogen and allergic reactions, has been widely used in clinical. The tissue culture experiments using murine spleen lymphocytes now demonstrate that this product can significantly promote the proliferation of splenic lymphocytes. The spleen lymphocyte DNA synthesis has a significant role in promoting. The stimulation index is about 9.3, the optimum stimulation dose is 50-60 μg/ml, and the optimal stimulation time is 48 hours. At the same time found that this product can also promote protein synthesis of splenic lymphocytes. At 50 μg/ml,