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目的:评价口服伊曲康唑与氟康唑治疗念珠菌性阴道炎成本-效果分析。方法:采用循证医学的方法收集临床资料,应用药物经济学的成本-效果分析法对口服伊曲康唑与氟康唑口服治疗念珠菌性阴道炎进行评价。结果:伊曲康唑与氟康唑口服治疗念珠菌性阴道炎治愈率分别为77.96%(69.24%,86.68%)、67.61%(65.95%,89.97%),C/E分别为4.02、0.51,ΔC/ΔE为26.98。结论:虽然伊曲康唑疗效优于氟康唑,但成本-效果分析表明,氟康唑更具成本-效果优势。
Objective: To evaluate the cost-effectiveness of oral administration of itraconazole and fluconazole in the treatment of Candida vaginitis. Methods: Evidence - based medicine was used to collect clinical data. Oral administration of itraconazole and fluconazole for the treatment of candida vaginitis was evaluated by the cost - effectiveness analysis method of pharmacoeconomics. Results: The cure rates of oral candida vaginitis with itraconazole and fluconazole were 77.96% (69.24%, 86.68%), 67.61% (65.95%, 89.97%), C / E were 4.02,0.51, ΔC / ΔE is 26.98. Conclusion: Although itraconazole is superior to fluconazole, cost-effectiveness analysis shows that fluconazole is more cost-effective.