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目的分析手足口病的流行病学及临床特征。方法回顾性分析在本院门诊及住院收治的892例诊断为手足口病患儿的流行病学、临床特征及治疗。结果 892例中男603例,女289例;1～3岁占73.3%。以3-6月份最多,占92%。786例有明确接触史。散居儿童占77.1%;492例(55.2%)患儿发热,其中37.5～38.0℃388例,占发热患儿的78.9%。403例先发热,1～2d出现皮疹,89例先出现皮疹,1～2d发热。患儿均有较典型的皮疹,以手掌、脚掌、臂部多见。803例出现口腔黏膜损害。882例(98.9%)为普通型,重症仅10例。WBC(4～10)×109L-1者710例,占79.6%。经抗病毒及对症治疗后,880例(98.6%)在1周内痊愈,3例转往上级医院治疗。结论本县手足口病发病率高,以1～3岁儿童多见,3-6月份为发病高峰,以普通型常见,临床表现典型。
Objective To analyze the epidemiology and clinical features of hand, foot and mouth disease. Methods The epidemiological, clinical characteristics and treatment of 892 children diagnosed as hand-foot-mouth disease were retrospectively analyzed in our hospital and hospitalized. Results There were 603 males and 289 females in 892 cases, 73.3% of whom were 1-3 years old. The most in March-June, accounting for 92%. 786 cases have a clear history of exposure. The scattered children accounted for 77.1%; 492 children (55.2%) had fever, of which 388 were 37.5-38.0 ℃, accounting for 78.9% of the children with fever. 403 cases of first fever, rash occurred 1 ~ 2d, 89 cases of rash first, 1 ~ 2d fever. Children have more typical rash, palms, soles, arms and more common. 803 cases of oral mucosal damage. 882 cases (98.9%) were normal type and severe cases were only 10 cases. 710 cases of WBC (4 ~ 10) × 109L-1, accounting for 79.6%. After anti-virus and symptomatic treatment, 880 cases (98.6%) recovered in 1 week and 3 cases were transferred to the higher-level hospital for treatment. Conclusion The incidence of hand, foot and mouth disease is high in this county. It is more common in children aged 1-3 years and peaked in March and June. It is common in common type and has typical clinical manifestations.