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库兴氏综合征是半个世纪以前(1932年)由著名的神经外科医师Cushing首先描述,以后人们就以他的名字命名这一临床综合征。他提出,由垂体的嗜碱细胞腺瘤或增生的分泌物增多,刺激两侧肾上腺皮质增生,因而引起该临床综合征。此后,人的糖皮质激素氢化考的松和促肾上腺皮质激素(ACTH)的特性得到确定。1961年Li-ddle及其同事肯定了Cushing所推测的双侧肾上腺皮质增生原发性疾病部位在垂体,他
Cushing’s syndrome was described half a century ago (1932) by the famous neurosurgeon Cushing, and later people named the clinical syndrome under his own name. He argues that the syndrome of basophilic adenoma or hyperplastic secretions of the pituitary, which stimulates both adrenal hyperplasia, causes this clinical syndrome. Since then, the properties of human glucocorticoid-hydrocortisone and adrenocorticotropic hormone (ACTH) have been determined. In 1961, Li-ddle and colleagues affirmed Cushing’s hypothesized predilection for bilateral adrenal hyperplasia in the pituitary gland