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本文报道了应用日本血吸虫肠相关抗原的间接血凝试验(IHA),对一个现存的和两个已经基本控制传播的血吸虫病流行区人群进行血清流行病学的调查结果。发现现存的流行区的人群抗体水平较其他两个地区明显为高。而且三个地区人群抗体阳性者的抗体滴度平均水平(GMRT)的年龄分布曲线也具不同的特征,现存流行区的低年龄组GMRT较高年龄组为高,而已经控制传播的地区低年龄组抗体水平则为0。认为分析当地低年龄组人群抗体水平,似可作为评价传播是否阻断的依据,并可作为监测流行趋势的工具。
This article reports the results of an indirect hemagglutination test (IHA) using the Schistosoma japonicum gut associated antigen in a serological epidemiological survey of an existing and two predominantly schistosomiasis-endemic areas. Antibody levels were found to be significantly higher in existing endemic areas than in the other two areas. In addition, the age distribution curve of GMRT in the antibody-positive individuals from three regions also had different characteristics. The prevalence of GMRT in the low-age group of the existing epidemic area was high, while that of the lower-prevalence GACT The group antibody level is 0. It is believed that analyzing the antibody levels of the local population in the lower age group may serve as a basis for evaluating whether the transmission is blocked and as a tool for monitoring epidemic trends.