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目的了解儿科肺炎链球菌的感染情况,分析肺炎链球菌的耐药性。方法选取梧州市红十字会医院儿科2015年3月—2016年6月收治的呼吸道感染患儿1052例,分别取标本进行痰细菌培养,并对所分离的肺炎链球菌进行药敏试验,统计肺炎链球菌检出率及其在不同季节的检出率,分析肺炎链球菌对红霉素、阿奇霉素、克林霉素、四环素、复方磺胺青霉素等抗生素的耐药性。结果 1052例患儿中肺炎链球菌感染99例,检出率为9.41%,其感染高发群体为婴幼儿。冬季检出率高于夏季、秋季与春季。药敏试验结果显示,肺炎链球菌对红霉素、阿奇霉素、克林霉素、四环素、头孢呋辛、复方磺胺均有较高的耐药性,其耐药率分别为95.95%、92.93%、89.90%、81.82%、78.79%、68.70%。结论肺炎链球菌引起的呼吸道感染高发于婴幼儿群体,冬季为高发季节,此病菌对红霉素等抗生素耐药性较强,临床应加强抗生素的使用管理,以减少肺炎链球菌对临床常用抗生素产生耐药性。
Objective To understand the infection of pediatric pneumococci and to analyze the drug resistance of Streptococcus pneumoniae. Methods 1052 children with respiratory tract infection admitted to Wuzhou Red Cross Hospital from March 2015 to June 2016 were selected for sputum bacterial culture. Streptococcus detection rate and its detection rate in different seasons, analysis of Streptococcus pneumoniae erythromycin, azithromycin, clindamycin, tetracycline, sulfamethoxazole and other antibiotics resistance. Results Of the 1052 cases, 99 cases were infected with S. pneumoniae, the detection rate was 9.41%. The most common infection was infants and young children. The detection rate in winter is higher than that in summer, autumn and spring. Susceptibility test results showed that Streptococcus pneumoniae showed high resistance to erythromycin, azithromycin, clindamycin, tetracycline, cefuroxime, and sulfamethoxazole, with drug resistance rates of 95.95% and 92.93%, respectively. 89.90%, 81.82%, 78.79%, 68.70%. Conclusion Streptococcus pneumoniae caused respiratory tract infections in infants and young children, winter is the high season, the bacteria resistant to erythromycin and other antibiotics, clinical should strengthen the use of antibiotics to reduce the use of Streptococcus pneumoniae clinical commonly used antibiotics Resistant.