Reversed-phase fused-core HPLC modeling of peptides

• 作 者: Matthias D'Hondt Bert Geva
• 机 构: DrugQualityandRegistration（DruQuaR）group,DepartmentsofMedicalImagingandPhysiology
• 出 处: 药物分析学报：英文版
• 发表日期: 2013年2期
• 关键词: C肽 反相 HPL 保留模型 建模 定量结构 预测能力 有机改性剂 Peptides Fused-core（core-shell core-enhanced p
• 基金项目: funded by a Ph.D.grant of ＂Institute for the Promotion of Innovation through Science and Technology in Flanders（IWT-Vlaanderen）＂（No.091241 for MD and 073402 for SVD）,the Special Research Fund of the G

Different fused-core stationary phase chemistries(C18,Amide,Phenyl-hexyl and Peptide ES-C18) were used for the analysis of 21 structurally representative model peptides.In addition,the effects of the mobile phase composition(ACN or MeOH as organic modifie