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目的探讨利用腺苷负荷门控心肌灌注显像的心功能参数评价陈旧性心肌梗死(OMI)患者心功能和预后的价值。方法OMI组16例,正常对照组18例,两组均进行99m锝标记甲氧基异丁基异腈(99Tcm-MIBI)腺苷负荷门控灌注显像,分析对比两组间的左室射血分数(LVEF)、舒张末期容积(EDV)、收缩末期容积(ESV)及左室壁运动情况。结果OMI组的LVEF(57.00±23.42)%低于正常对照组(76.44±11.68)%,而左室容积参数EDV明显大于正常对照组(133.00±87.96)ml vs(67.11±19.21)ml和ESV(73.97±83.15)ml vs(17.17±11.36)ml;三维心室运动图像观察发现9例(56.3%)OMI患者出现室壁运动减弱;两组间心功能参数经统计学分析差异均有统计学意义(均P<0.05)。结论腺苷负荷门控心肌灌注显像中测得的功能参数是评价左室功能的重要指标,其对陈旧性心肌梗死患者的心功能评价、疗效观察及预后判定均有重要意义。
Objective To investigate the value of cardiac function and prognosis in patients with old myocardial infarction (OMI) using cardiac function parameters of adenosine-loaded gated myocardial perfusion imaging. Methods 16 cases of OMI group and 18 cases of normal control group were performed 99mTc-MIBI adenosine stress gated perfusion imaging in both groups. The left ventricular ejection fraction (LVEF), end-diastolic volume (EDV), end-systolic volume (ESV) and left ventricular wall motion. Results The LVEF of OMI group was significantly lower than that of normal control group (57.00 ± 23.42% vs 76.44 ± 11.68% vs 83.00 ± 87.96 ml vs 67.11 ± 19.21 ml vs ESV ( 73.97 ± 83.15) ml vs (17.17 ± 11.36) ml, respectively. In 9 cases (56.3%) of OMI patients, wall motion was found to be decreased by three-dimensional ventricular motion imaging. The statistical analysis of cardiac function parameters between the two groups showed statistically significant differences All P <0.05). Conclusions The functional parameters measured in adenosine-loaded gated myocardial perfusion imaging are important indexes for evaluating left ventricular function. They are important for evaluating cardiac function, curative effect and prognosis in patients with old myocardial infarction.