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目的评估乳腺癌相关抗原（CA15-3）在原发性乳腺癌病人的术前预估中的价值。方法通过微粒子免疫分析法（MEIA）对518例乳腺癌病人的CA15－3血清水平进行研究。结果发现其水平与疾病分期、肿瘤大小、淋巴结状况、转移癌的出现和淋巴细胞渗入肿瘤密切相关，CA15－3的血清水平＞40U/ml对晚期癌症有85％的阳性预测值，其水平在各期乳腺癌的术后均有下降。结论在原发性乳腺癌的术前评估中应对CA15－3进行常规检测。
Objective To assess the value of breast cancer associated antigen (CA15-3) in the preoperative estimation of patients with primary breast cancer. Methods The serum levels of CA15-3 in 518 patients with breast cancer were studied by microparticle immunoassay (MEIA). The results showed that the levels were closely related to the stage of the disease, the size of the tumor, the status of lymph nodes, the appearance of metastatic cancer and the infiltration of lymphocytes into the tumor. The serum level of CA15-3> 40U / ml had 85% positive predictive value for advanced cancer, All postoperative breast cancer decreased. Conclusion CA15-3 should be routinely tested in preoperative evaluation of primary breast cancer.