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Gershlick 和 Richardson 认为(见本期第73页),药物洗脱支架较金属裸支架的血栓形成风险增高是因为药物洗脱支架暴露时间延长所致。我们认为支架血栓形成部分是由于患者对氯吡格雷和阿司匹林的低反应性,而且在介入治疗术前就要确定这部分患者并给予替代的口服抗血小板药物治疗策略。
According to Gershlick and Richardson (see page 73 of this issue), the increased risk of thrombosis of drug-eluting stents versus metal-bare stents is due to extended drug-eluting stent exposure. We believe that stent thrombosis is partly due to the patient’s low reactivity to clopidogrel and aspirin, and this group of patients is prescribed prior to intervention and given an alternative oral anti-platelet therapy strategy.