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目的了解住院病人多重耐药菌医院感染情况,研究控制方法。方法采用细菌分离鉴定技术和药敏试验方法,对某医院2010-2012年住院病人送检标本进行细菌学检测与结果分析,对检出多重耐药菌株的病例实施监测和管理。结果该医院连续3年住院病人103 022例,诊断MDROs医院感染患者679例,感染率为0.66%;每个年度MDROs医院感染例次感染率依次为0.85%、0.68%和0.49%。医院感染部位以下呼吸道居首位,医院感染病例最多的是神经外科。医院感染MDROs菌株中,居前四位的是鲍曼不动杆菌、大肠埃希菌、MRSA和肺炎克雷伯菌。结论该医院多重耐药菌医院感染率呈现逐年下降趋势,对多重耐药菌监测和防控措施到位,应有重点地开展相关重点部位的监测和管理。
Objective To understand the multi-drug resistant inpatients hospital infection, research methods of control. Methods Bacterial isolation and identification techniques and drug susceptibility testing methods were used to carry out bacteriological examination and analysis of inpatients from 2010 to 2012 in a hospital. The detection and management of cases with multi-drug resistant strains were carried out. Results The hospital had 3,022 inpatients for 3 consecutive years and 679 patients were diagnosed as MDROs. The infection rate was 0.66%. The annual infection rates of MDROs were 0.85%, 0.68% and 0.49% respectively. The respiratory tract below the site of nosocomial infection ranks first, and the largest number of nosocomial infections is neurosurgery. Of the top four MDROs of hospital-acquired infections, Acinetobacter baumannii, Escherichia coli, MRSA and Klebsiella pneumoniae were the top four carriers. Conclusion The hospital infection rate of multidrug-resistant bacteria in this hospital shows a declining trend year by year. Monitoring and controlling multi-drug resistant bacteria are in place. Therefore, monitoring and management of relevant key parts should be carried out emphatically.