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[目的]了解扬州市手足口病的流行情况与病原分布情况,为制定预防和控制策略提供依据。[方法]对扬州市2009年手足口病发病资料与部分临床诊断病例咽拭子、肛拭子标本肠道病毒核酸检测资料进行分析。[结果]2009年扬州市报告手足口病病例5 150例,其中3例为重症,无死亡病例。年发病率112.00/10万,4区为186.16/10万,4县为85.31/10万(P<0.01);男性为140.30/10万,女性为83.44/10万(P<0.01)。5 150例病人中,4月发病的占25.81%,10~12月发病的占26.06%;1月龄至6岁的占95.07%,7~14岁儿童占4.68%,14岁以上及成人占0.25%;散居儿童占38.33%,幼托儿童占57.28%,学生占4.12%,其他占0.27%。检测143例手足口病病例标本,EV通用、EV71、CoxA 16阳性率分别为74.13%、51.05%、2.80%。[结论]2009年扬州市手足口病发病率较高,发病与病原学特征无明显变化。
[Objective] To understand the prevalence and pathogen distribution of HFMD in Yangzhou, and provide the basis for formulating prevention and control strategies. [Method] The detection data of enterovirus nucleic acid of throat swabs and anal swab specimens from 2009 to 2009 and the clinical diagnostic data of hand-foot-mouth disease in Yangzhou city were analyzed. [Results] In 2009, Yangzhou City reported 5 150 cases of hand-foot-mouth disease, of which 3 cases were severe and no deaths were found. The annual incidence was 112.00 / 100000, with 186.16 / 100000 in 4 districts and 85.31 / 100000 in 4 counties (P <0.01). There were 140.30 / 100000 males and 83.44 / 100000 females (P <0.01). Of the 5 150 patients, 25.81% were reported in April and 26.06% were reported in 10-12 months. 95.07% were from 1 month to 6 years old, 4.68% were from 7 to 14 years old, and were over 14 years old and adults 0.25%; scattered children accounted for 38.33%, childcare children accounted for 57.28%, students accounted for 4.12%, others accounted for 0.27%. The detection of 143 cases of hand, foot and mouth disease cases, EV universal, EV71, CoxA16 positive rates were 74.13%, 51.05%, 2.80%. [Conclusion] The incidence rate of hand-foot-mouth disease in Yangzhou was high in 2009 with no significant changes in the incidence and etiology.