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测定长沙地区５９３名成年人的血浆脂蛋白（ａ）［Ｌｐ（ａ）］水平。结果表明：Ｌｐ（ａ）水平程偏态分布，对数转换可使其分布正态化。２０９例冠心病患者中，血浆Ｌｐ（ａ）水平＞１００ｍｇ．Ｌ－１者占该组的３４．８％，而在３０５名正常对照组者中仅占１７．３％（Ｐ＜０．０１）。冠心病组的Ｌｐ（ａ）水平亦显著高于正常对照组。多因素逐步回归分析发现血浆Ｌｐ（ａ）水平与冠心病呈正相关。提示血浆Ｌｐ（ａ）水平与冠心病发病密切相关，是冠心病重要的独立危险因素。
Plasma lipoprotein (a) [Lp (a)] levels were measured in 593 adults in Changsha. The results show that the Lp (a) horizontal distribution is skewed, and its logarithmic transformation can make its distribution normalized. Of 209 patients with coronary heart disease, plasma Lp (a) levels> 100 mg. L-1 accounted for 34.8% of the group, while only 17.3% of 305 normal controls (P <0.01). Coronary heart disease group Lp (a) level was also significantly higher than the normal control group. Multi-factor regression analysis showed that plasma Lp (a) level was positively correlated with coronary heart disease. It is suggested that the level of plasma Lp (a) is closely related to the incidence of coronary heart disease and is an important independent risk factor for coronary heart disease.