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目的观察硬膜外与腰硬联合麻醉两种模式在分娩镇痛中的不良反应。方法选择单胎足月初产妇100例,随机分为硬膜外分娩镇痛组(E组)50例,腰硬联合镇痛组(S组)50例。观察两组产妇运动神经阻滞、皮肤瘙痒、恶心呕吐不良反应的发生情况。结果 S组产妇皮肤瘙痒发生率明显高于E组(P<0.05),但均为轻度,S组恶心呕吐发生率高于E组(P<0.05)。结论蛛网膜下腔使用舒芬太尼联合硬膜外腔镇痛模式可以快速、有效进行镇痛,但是瘙痒和恶心呕吐的副作用发生率较高。
Objective To observe the adverse reactions of epidural and combined spinal and epidural anesthesia in labor analgesia. Methods 100 single-fetus term mothers were selected and randomly divided into epidural labor analgesia group (E group) 50 cases, combined spinal and epidural analgesia group (S group) 50 cases. The incidence of motor block, pruritus and nausea and vomiting were observed in two groups. Results The incidence of skin pruritus in group S was significantly higher than that in group E (all P <0.05), but both were mild. The incidence of nausea and vomiting in group S was higher than that in group E (P <0.05). Conclusions Subarachnoid administration of sufentanil combined with epidural analgesia provides rapid and effective analgesia, but there is a high incidence of side effects of itching and nausea and vomiting.